As I mentioned
to Chairman Regula, that treatment of yesterday is here today; it is
hyperbaric oxygen therapy. Interestingly, and seemingly
paradoxically, this same treatment that is potentially so effective
acutely in combination with radiation therapy is by far the most
effective therapy for treatment of the late effects of radiation
therapy.
In now 67 of 74
worldwide studies on HBOT in the treatment of radiation injury to
multiple different areas and organs of the human body the results
were strongly positive (Feldmeier JJ, Hampson NB. A Systematic
Review of the Literature Reporting the Application of Hyperbaric
Oxygen Prevention and Treatment of Delayed Radiation Injuries; An
Evidence Based Approach. Undersea and Hyper Med, 2002;29(1):4-30.
While we have
evidence for the great potential of HBOT in acute injury my concern
today is for the millions of individuals in the United States and
hundreds of millions of individuals worldwide who suffer from
chronic brain injury of all types. Given the information above about
the nature of acute brain injury, namely, the deprivation of oxygen
and blood flow, and the common underlying process of secondary
injury in so many of these conditions, it is no surprise that many
chronic conditions, especially of the brain, are characterized by
low oxygenation and blood flow.
In l990 I
realized that we could treat this chronic injury by discovering that
a lower dose of HBOT pioneered in South Florida by Dr. Richard
Neubauer in stroke and multiple sclerosis patients could be
successfully applied to, once again, the classic accepted condition
for HBOT, decompression illness of divers.
I found that
divers who had failed standard United States Navy HBOT or divers who
presented weeks to months after their diving accident with
decompression illness of the brain could be permanently improved
neurologically, cognitively, and emotionally and return to a
functional high quality life. My partners, Drs. Keith Van Meter and
Sheldon Gottlieb, simultaneously were proving this in brain injured
boxers.
With these two
doctors I then extended the findings in divers to patients with now
over 50 different neurological conditions using SPECT brain blood
flow imaging before and after a single HBOT to predict which
patients had injured brain tissue that could respond to a course of
HBOT.
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